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Sleep duration and risk of stroke mortality among Chinese adults: the Singapore Chinese Health Study

Identifieur interne : 001271 ( Main/Exploration ); précédent : 001270; suivant : 001272

Sleep duration and risk of stroke mortality among Chinese adults: the Singapore Chinese Health Study

Auteurs : An Pan ; Deidre Anne De Silva ; Jian-Min Yuan ; Woon-Puay Koh

Source :

RBID : PMC:4102627

Descripteurs français

English descriptors

Abstract

Background and Purpose

Prospective relation between sleep duration and stroke risk is less studied, particularly in Asians. We examined the association between sleep duration and stroke mortality among Chinese adults.

Methods

The Singapore Chinese Health Study is a population-based cohort of 63,257 Chinese adults aged 45-74 years enrolled during 1993 through 1998. Sleep duration at baseline was assessed via in-person interview, and death information during follow-up was ascertained via record linkage with the death registry up to December 31, 2011. Cox proportional hazard models were used to calculate hazard ratios (HRs) with adjustment for other comorbidities and lifestyle risk factors of stroke mortality.

Results

During 926,752 person-years of follow-up, we documented 1,381 stroke deaths (322 from hemorrhagic and 1,059 from ischemic or non-specified strokes). Compared to individuals with 7 hours/day of sleep, the multivariate-adjusted HR (95% confidence interval) of total stroke mortality was 1.25 (1.05-1.50) for ≤5 hours/day (short duration), 1.01 (0.87-1.18) for 6 hours/day, 1.09 (0.95-1.26) for 8 hours/day, and 1.54 (1.28-1.85) for ≥9 hours/day (long duration). The increased risk of stroke death with short (1.54; 1.16-2.03) and long duration of sleep (1.95; 1.48-2.57) was seen among subjects with a history of hypertension, but not in those without hypertension. These findings were limited to risk of death from ischemic or non-specified stroke, but not observed for hemorrhagic stroke.

Conclusions

Both short and long sleep durations are associated with increased risk of stroke mortality in a Chinese population, particularly among those with a history of hypertension.


Url:
DOI: 10.1161/STROKEAHA.114.005181
PubMed: 24743442
PubMed Central: 4102627


Affiliations:


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<title>Background and Purpose</title>
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